Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noo syndrome, and juvenile myelomonocytic leukemia.
GTPase NRas; N-ras protein part 4; neuroblastoma RAS viral (v-ras) oncogene homolog; NRAS neuroblastoma RAS viral (v-ras) oncogene homolog NS6 CMNS NRAS1 ALPS4 NCMS N-ras; Transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
Cat # 16356794
100 µl
Cat # 16366794
100 µl
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